Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing

Osimertinib, which is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, is an important anticancer drug because of its high efficacy and excellent safety profile.However, resistance against osimertinib is inevitable; therefore, therapeutic strategies to overcome The Border South the resistance are needed.Doxazosin, a cl

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Inspection of Defective Glass Bottle Mouths Using Machine Learning

In this study, we proposed a method for detecting chips in the mouth of glass bottles using machine learning.In recent years, Japanese cosmetic glass bottles have gained attention for their advancements in manufacturing technology and eco-friendliness through the use of recycled glass, leading to an increase in the volume of glass bottle exports ov

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